My Auto-blog blueprint!
1). Buy domain with topic keyword in it.
2). Install latest WordPress, on new domain.
3) Setup WordPress options (permalinks, general, discussion).
4). Setup WordPress theme header image and background color.
5). Create new users for your site, about 5 or more, (these users will become your site Authors).
6). Add some links and widgets to your homepage (preferably non-affiliate links). eg: Stat-counters, or a link to a manufacturer.
7). Install latest WP-robot plugin on your WordPress site.
8). Setup options for WP-robot (Save images, Authors, Yahoo API).
9). Modify WP-robot module template and post template (important for more unique content).
10). Add campaigns to WP-robot, make sure you use the delay feature (I'm currently using a delay of +10hrs per campaign so campaign 49 would have an extra delay of 490hrs)
And that's it, wait till you have over 1k pages indexed into Google then start to add one or two adverts either directly into the theme in single-post HTML, or using a widget!
DON'T PUT AFFILIATE LINKS ON HOME PAGE TILL YOU HAVE GOOGLE PAGE RANK!
Using these methods most of my sites are earning $1-$2 per day after 2-3 months!
I have tried other methods like multi-sites, but if you are not careful your sites can be either de-indexed or SERP penalized by Google very quickly! My advice is to experiment with different setups, but the above is my blueprint for 'single domain' successful auto-blogs!